Healthy diet and exercise in Alzheimer’s studies

older joggersNew research finds eating healthy, moderate activity and genes that don’t predispose you to dementia is a recipe for preserving cognitive function as you age, according to four new studies that were presented at the Alzheimer’s Association annual conference, in Vienna.

The findings echo other research suggesting that clean living can safeguard mental sharpness. However, one of the studies did contain a surprise finding – that strenuous exercise could actually impair cognitive skills later in life.

That should be viewed, for now, with some scepticism, said William Thies, chief medical and scientific officer of the Alzheimer’s Association.
“That’s something I wouldn’t take on faith from a single study,” he stressed.

In one study, Heidi Wengreen, an assistant professor of nutrition at Utah State University, asked 3,831 adults, aged 65 and older, to complete a food survey. They then tested their cognitive skills over an 11-year period, beginning in 1995.

The researchers looked to see how well the participants followed the DASH diet, an eating regimen that protects against hypertension and heart trouble. Those who followed the DASH diet more closely had higher scores on the cognitive tests at the start of the study and over time, Wengreen found.

Although Wengreen said more study was needed, “I believe there is plenty of evidence to suggest that diet plays a role in delaying cognitive decline and perhaps preventing Alzheimer’s disease among the elderly.”

Two further exercise studies found staying active can also help.

In one study, Deborah E. Barnes, of the University of California, San Francisco, followed more than 3,000 adults aged 70 to 79. Those who were sedentary had the lowest level of cognitive function at the start and higher rates of decline over the course of the seven-year study.

Another study in which researchers followed nearly 1,800 men and women aged 60 and older found that physical activity boosts cognitive function, except in those who carried the so-called Alzheimer’s gene, known as APOE-e4.

Controversially a fourth study found moderate long-term exercise helped cognitive skills later, but that strenuous long-term exercise might hamper them.

Mary Tierney, a professor of family and community medicine at the University of Toronto, evaluated 90 women, aged 50 to 63, taking into account their long-term activity, both moderate and strenuous. Each woman got a score for strenuous and moderate activity.

Strenuous activities included swimming laps, aerobics, calisthenics, jogging, running, basketball, biking on hills and racquetball. Moderate included brisk walking, golf, volleyball, cycling on level streets, tennis and softball.

“The average long-term strenuous activity was for 2.5 hours a week, and the average long-term moderate activity was 3.2 hours a week,” Tierney said.

“The worst groups [on cognitive function tests] were the ones highest in strenuous and lowest in moderate,” she said.

Exactly why the link showed up isn’t known, she said. But it may be that the strenuous exercise is lowering estrogen levels and lowered estrogen lowers cognitive skills. “Estrogen is bad for breast cancer, but good for the brain,” Tierney explained.

It’s impossible to say how much exercise is too much, Tierney added.

Given the relatively small size of the project and the fact that it studied only women, we feel that much more research is required before any such link could be seriously suggested – interesting though.

Source: The Alzheimer’s Society

4 thoughts on “Healthy diet and exercise in Alzheimer’s studies

  1. Any research that can provide additional insight into Alzheimer’s is critical to finding a cure. It is also important for patients and families affected by Alzheimer’s to consider participating in clinical studies. One such study is the ICARA Study (www.icarastudy.com), whose goal is to explore if an investigational drug, called Bapineuzumab, can help slow the progression of Alzheimer’s Disease. Clinical studies that test new treatments are the best chance we have for fighting this disease.

  2. I’ve always been one to follow Alzheimer’s and will do anything to keep myself healthy so I can avoid it many years down the road. With the amount of medical problems out there in the world it is going to be hard to find a cure for them all, but with a little effort and support I know it will happen.

    Thanks for the post.

    Christine

  3. Exercise and dieting is something I practice regularly and I am glad to see that it could really benefit me down the road. Thanks for sharing this.

  4. Exercise for brain like physical activities slows brain atrophy like Alzheimer’s disease according to many studies. I liked the information in your blogs regarding this..
    Thank u!

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